Compared with non-cachexia patients, patients who were later diagnosed with cachexia had lower BMI, lower ALB content, lower lymphocyte count and PNI score, advanced TNM staging, worse Nutritional Risk Screening 2002 (NRS2002 score), higher levels of tumor markers (CEA, CA199 and CA125), higher SII score and D-dimer, prolonger prothrombin time (PT). The gene discussed is F2; the disease is neoplasm.