The venous disease presents with recurrent attacks of venous thrombosis while arterial disease presents with the formation of aneurysms in the aorta, pulmonary arteries, and visceral arteries.8 There are many steps in the mechanism of thrombosis, one of which is the disruption of the combination between VWF and ADAMTS-13 (a disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13). This evidence concerns the gene VWF and Venous thrombosis.