IFNAR1 and neoplasm: The type-1 interferon response leads to autocrine activation of IFNAR (interferon α/β receptors), resulting in CXCL9 (C-X-C motif chemokine ligand 9) and CXCL10 (C-X-C motif chemokine ligand 10) production, which subsequently stimulates T lymphocyte infiltration into the tumor (14).