reported that the expression level of long-chain specific lipoyl coenzyme A synthetase 4 (ACSL4) was significantly reduced in synovial and fibroblast-like synovial cells (FLS) from patients with RA, while the expression levels of ferritin heavy chain 1 (FTH1), GPX4, and solute carrier family 7 member 11 (SLC7A11) expression levels were comparatively increased (89). Here, SLC7A11 is linked to rheumatoid arthritis.