TNF and rheumatoid arthritis: As observed in Figure 6D, the decay rate of circ-CBLB was the lowest in the RA-FLS + M0 group and the highest in the RA-FLS + M0 + TNF-α + pcDNA3.1-WTAP group, and there were no differences in the decay rate among the RA-FLS + M0 + TNF-α + pcDNA3.1-NC, RA-FLS + M0 + TNF-α + si-NC, and RA-FLS + M0 + TNF-α groups.