CD4 and nocardiosis: His symptoms fully resolved, with no recurrence of cough or asthma-like exacerbations. Although Nocardia infections are commonly associated with immunosuppression, typically occurring in patients with solid organ or hematopoietic cell transplants, chronic glucocorticoid use, malignancy, or HIV with low CD4 counts, approximately one-third of cases are reported in immunocompetent individuals.