Chong DWL et al. also found similar findings suggesting that the risk of pulmonary fibrosis does not increase even with increased platelet count,17 while Michael G. et al. reported that indirectly activated platelets release fibrogenic factors such as PDGF and TGF-α, which caused fibrous tissue deposition, but did not confirm the association between platelet activation and the occurrence of pulmonary fibrosis.28 A negative correlation with platelet count, critical platelet level, MPV, and PDW was reported in patients who subsequently developed pulmonary fibrosis. This evidence concerns the gene TGFA and pulmonary fibrosis.