Additionally, some researchers have proposed the feasibility of sGC stimulators or activators as a new potential method for conjunctiva fibrosis or pulmonary fibrosis through experimental studies based on the effect of sGC inhibiting TGF-β pathway on tissue fibrosis and cell proliferation (Li et al., 2023; Fioretto et al., 2024). This evidence concerns the gene SGCB and fibrosis.