Researchers isolated platelets and performed RNA-seq detection, and found that compared with healthy people, MS caused 1,249 changes in platelet RNA profiles, including increased expression of Epithelial-Stromal Interaction 1 (EPSTI1) and IFN alpha inducible protein 6 (IFI6), and decreased expression of Ribosomal protein S6 kinase A3 (RPS6KA3), which is consistent with the reported inflammatory characteristics in the blood of MS patients. Here, RPS6KA3 is linked to myeloid sarcoma.