Our findings will inform future clinical preventative strategies including early diagnosis of diabetes and its complications; intensified management of hyperglycaemia with use of newer treatments such as (e.g. GLP 1 receptor agonists and SGLT 2 inhibitors); intensive, target‐driven management of cardiovascular risk factors (hypertension, hyperlipidaemia, smoking cessation, tailored exercise programmes) and reducing inequality in health by, for example, one‐stop screening services in deprived areas to increase the uptake of NICE recommended annual health checks.41, 42. This evidence concerns the gene GLP1R and Hyperglycemia.