KDF1 and ectodermal dysplasia syndrome: Segregation analysis in 9 affected (III-8, IV-1, IV-8, IV-9, IV-10, IV-12, V-15, V16, V-24) and 10 unaffected (III-3, III-10, IV-2, IV-11, V-1, V-17, V-18, V-19, V-20, V-23) members of this family confirmed that this KDF1 variant segregated with the dental phenotype in otherwise normal family members with no ectodermal dysplasia or other recognizable syndrome (Figures 1, 2, 4).