Results did not support the presence of interaction with these two conditions at any locus after multiple testing control, despite nominally significant P-values observed for SNP interaction with hyperthyroidism at SHROOM3 (P = 0.03) and with hypothyroidism at PIP5K1B (P = 0.03) and GAB2 (P = 0.04; S7 Table in S2 File). Here, GAB2 is linked to hypothyroidism.