MCL1 and cancer: Myeloid cell leukaemia-1 (Mcl-1) is another member of the Bcl-2 family that may inhibit apoptosis in senescent cells, Mcl-1 is upregulated in senescent cancer cells and the Mcl-1 inhibitor S63845 eliminates senescent cancer cells more effectively than navitoclax (Troiani et al, 2022).