HAVCR2 and neoplasm: Tumor models expressing the nominal antigen ovalbumin (LLCova and B16ova) had a slightly higher proportion of T cell receptors reactive to ovalbumin-immunodominant peptide SIINFEKL in B16ova compared with LLCova and similar levels of exhaustion markers such as Tim-3, PD-1, and Lag-3 (Figure 2D).