Interestingly, the dominant CD45+ hematopoietic cell type within the CD45+ IFN-γ+ and TNF-α+ population was CD11b+ myeloid cells (Figure 5A), which are enriched in the CD8+ T cell–sufficient tumor microenvironment, as described earlier (Supplemental Figure 3B). The gene discussed is ITGAM; the disease is neoplasm.