CD8A and neoplasm: Although there was only a modest trend for decreased CCR5 chemokine production by CD8+ T cells in the tumor bed of LLC Ifng-KO tumor–bearing mice compared with the parental LLC-bearing mice (Supplemental Figure 6G), there was an overall decrease of Treg infiltration into the LLC Ifng-KO tumor bed compared with the parental LLC (Figure 6G).