These have focussed mainly on the production of gastrin that can be associated with Zollinger-Ellison syndrome and multiple endocrine neoplasia type 1 (MEN1) syndrome (15–17) or of somatostatin (18) that may be associated with a unique psammomatous tumor in patients with neurofibromatosis (19). Here, GAST is linked to multiple endocrine neoplasia type 1.