Anti-inflammatory tumor-associated macrophages (TAMs; CD45+CD11b+Ly6G–Ly6ClowCD206+) decreased in the LLO-SK multipleinjection +mannose group (p <.0001) and LLO +mannosegroup (p = 0.041), which highlighted the abilityto decrease these cell populations that are key players in tumor progressionand contribute to a protumoral phenotype. This evidence concerns the gene PTPRC and neoplasm.