The final candidate lncRNAs studied in more detail were BDNF-AS, GMDS-AS1, and XLOC_030781 that ranked highly (among the top 10) in both CRISPRi screens: BDNF-AS is located on chromosome 11 (genomic coordinates from GRCh38.p14 assembly; chromosome 11: 27,506,830-27,698,231 forward strand) and has been implicated in various cancer types. The gene discussed is GMDS; the disease is cancer.