TRPV4 and open-angle glaucoma: The threefold increase in TRPV4 transcription and responsiveness to GSK101 was observed at POAG-relevant TGFβ2 concentrations (in AH, ~0.2–3.2 ng/ml; Agarwal et al., 2015), with a time course that mirrored facility reduction in human eyes treated with exogenous cytokine (Gottanka et al., 2004).