Additionally, in head and neck squamous carcinoma cells, BAY‐876 enhanced apoptosis when combined at low concentrations with bitter‐taste‐receptor agonists and reduced tumor necrosis factor alpha‐induced interleukin‐8 production from tumor cells in vitro, implying that GLUT1 inhibition may influence the tumor microenvironment and antitumor immunity [142]. The gene discussed is TNF; the disease is neoplasm.