Previous research has suggested that BMP2 and BMP4 can induce the transdifferentiation of myofibroblasts into adipocyte‐like cells that store lipids.[65] In pancreatic cancer, for example, tumor cells have been shown to secrete BMP2, promoting the differentiation of lipid‐rich CAFs.[66] In this context, we found that BMP2 may play a role in promoting the transformation of cancer‐associated myofibroblasts into the MMP11+ mCAFs subpopulation. Here, MMP11 is linked to familial pancreatic carcinoma.