demonstrated that a subpopulation of bladder CAFs (SLC14A1+ CAFs), promotes cancer stemness in bladder cancer cells via the WNT5A signaling pathway, thereby contributing to tumor aggressiveness and chemotherapy resistance.[25] In this study, we identified a distinct mechanism whereby MMP11+ mCAFs regulate the migration of ESM1+ tEC through a WNT5A‐mediated ncWNT signaling axis. The gene discussed is SLC14A1; the disease is urinary bladder carcinoma.