On the contrary, others have been shown to act as tumor suppressors, either boosting tumor suppressor pathways or counteracting the actions of oncoproteins, such as RPS6 [15], RPL11 [16], RPL22 [17], etc. Particularly, RPL35A, a gene responsible for coordinating the 60S large ribosomal subunit protein and located on chromosome 3q29‐qter [18], was widely identified to participate in Diamond‐Blackfan anemia [19, 20]. The gene discussed is RPL22; the disease is neoplasm.