GSDMD and mastitis: Gasdermin D (GSDMD) is a key execution protein in the PANoptosis pathway, and the release of its N‐terminal (NT), which causes the rupture of the cell membrane as well as the release of a large number of pro‐inflammatory factors, exacerbating the rapid progression of inflammatory responses.[8] In addition, GSDMD activation is closely related to the barrier damage triggered during inflammatory diseases.[9] Therefore, analyzing the relationship between GSDMD activation and BMB damage in mastitis disease is important for curing mastitis.