Previous studies have shown that isocitrate dehydrogenase (IDH)‐mutant AML cells upregulate glycolysis via 2‐hydroxyglutarate (2‐HG), potentially increasing glycerol uptake to meet heightened bioenergetic and biosynthetic requirements (Savino and Stuani 2024). This evidence concerns the gene IDH3A and acute myeloid leukemia.