APOE and Schnyder corneal dystrophy: This is particularly important for at-risk populations such as Apolipoprotein E (APOE) ε4 allele carriers (Harris, 2024), those with a family history of dementia (Lee et al., 2022), and those at an early stage of cognitive decline, known as Subjective Cognitive Decline (SCD) (Jessen et al., 2014).