Cyanidin-3-glucoside, a type of anthocyanin, exhibits therapeutic effects in RA by inhibiting lipopolysaccharides-induced inflammation in human fibroblast-like synoviocytes through the suppression of NF-κB and MAPK signaling pathways and by reducing disease severity and inflammatory cytokine levels in a CIA mouse model (65). Here, NFKB1 is linked to rheumatoid arthritis.