In our sample, patients meeting clinical criteria for depression showed average pre-treatment scores in the moderate range (PHQ-9: M = 15.55, SD = 3.76; GAD-7: M = 13.43, SD = 2.87), falling below thresholds typically used to define high symptom severity (PHQ-9 ≥20; GAD-7 ≥15). This evidence concerns the gene GAD1 and depressive symptom measurement.