Supplementary Table S1 showed the univariate Cox regression analysis for MACE, indicating that age, hypertension, diabetes, AF, CKD, antihypertensive drugs, hypoglycemic agents, SBP, Lp(a), Log10Lp(a), eGFR, BNP, and multivessel disease were all significantly associated with MACE occurrence (P < 0.05). The gene discussed is NPPB; the disease is chronic kidney disease.