Study (Fondevila et al., 2022) found that CPT1A was highly expressed in patients with liver fibrosis and activated HSC in mice, which was positively correlated with the degree of liver fibrosis, and in fibrotic hepatocytes, CPT1A overexpression increased FAO, which stimulated the production of ROS, and ultimately the activation of HSC, whereas the inhibition/specific knockdown of CPT1 blocked the activation of HSC, which then interfered with the progression of liver fibrosis. Here, CPT1A is linked to Hepatic fibrosis.