STING1 and STING-associated vasculopathy with onset in infancy: Keskitalo S et al. identified a previously undescribed gain-of-function mutation (G207E) in STING, characterized by a distinctive clinical profile including hair loss, light sensitivity, thyroid abnormalities, and SAVI-associated features such as livedo reticularis, vasculitis of the skin, nasal septum perforation, facial redness, and increased susceptibility to bacterial pathogens.