BCL2 and acute lymphoblastic leukemia: There was heterogeneous upregulation of BCL2 Apoptosis Regulator (BCL2), BCL2 Like 1 (BCL-xL), and MCL1 Apoptosis Regulator, BCL2 Family Member (MCL-1) in mouse (Figure 5A) and human (Figure 5B) T-ALL with DNMT3A mutations.