PRRT2 and cancer: For example, in smooth muscle cells, PKC participates in cell contraction and relaxation (Kim et al., 2013); in cancer cells, PKC participates in cell proliferation and invasion (He et al., 2022; Su et al., 2013); in mammalian oocytes, PKC participates in the fertilization process of oocytes (Halet, 2004); in immune cells, PKC participates in immune regulation (Gruber et al., 2009); in nerve cells, PKC participates in the regulation of mental diseases (Saito and Shirai, 2002).