We predicted the target genes of has‐miR‐106a‐5p, intersected them with the final 236 DEGs, screened them according to the criteria of negative regulation between miRNA expression levels and gene expression levels, and finally obtained four differentially expressed target genes in PCOS patients: LDLR, RUNX1, FICD, and STAC2 (Table 4). This evidence concerns the gene LDLR and polycystic ovary syndrome.