ESR1 and polycystic ovary syndrome: Our study also revealed that variants rs2234693 (T>C, G) in ESR1 (Estrogen Receptor 1) and rs6166 (C.2039 >G; p.Asn680Ser) in FSHR genes had similar allele frequencies, i.e, 14/22 and 13/22 respectively, among the PCOS patients screened.