CTPA: computed tomography pulmonary angiography; DIC: disseminated intravascular coagulation; LV: left ventricular; RV: right ventricular; MR: mitral regurgitation; AFE: amniotic fluid embolism; PPCM: peripartum cardiomyopathy; PE: pulmonary embolism; EF: ejection fraction; BNP: B-type natriuretic peptide. The gene discussed is NPPB; the disease is pulmonary embolism.