PCSK2 and type 2 diabetes mellitus: Glycine (p < 0.0001), high density lipoprotein (HDL) phospholipid (p = 0.001; HDPL), SPC2 (p < 0.0001), SPC3 (p = 0.002) and the SPC/Glyc ratio (p < 0.0001) (Figure 3) were lower in T2DM when compared with healthy controls.