The apolipoprotein B100/apolipoprotein A1 ratio is positively associated with T2DM prevalence (i.e., higher levels of apolipoprotein B100 and lower levels of apolipoprotein A1), owing to a dysregulation in the mechanistic effects of apolipoprotein B100 to inhibit lipolysis and/or apolipoprotein A1 to increase the uptake of glucose into skeletal muscle tissue and exert anti‐inflammatory actions (Gao et al., 2021). Here, APOA1 is linked to type 2 diabetes mellitus.