Insulin resistance indices in the depression group (HOMA-IR: 3.05 vs. 2.49; LAP: 48.79 vs. 38.49; TyG: 8.71 vs. 8.55) and inflammatory markers (white blood cell count, neutrophil count, platelet count) were significantly elevated, while serum albumin levels were lower. This evidence concerns the gene ALB and Insulin resistance.