The KRASG12V/MYC expressing tumor cells showed further characteristic features of cancer cells [30, 31], such as a decreased cell size and cytoskeletal remodeling (Fig. 1B, Supplementary Fig. S1A), increased migration (Supplementary Fig. S1B, C) and transwell invasion (Supplementary Fig. S1D, E). The gene discussed is MYC; the disease is cancer.