While some thrombocytopenic disorders (e.g., MYH9‐related disorders, MYH9RD) can have normal aggregation findings, others have pathognomonic maximal aggregation (MA) abnormalities, including congenital Bernard–Soulier syndrome (BSS), ITGA2/ITGB3‐related thrombocytopenia (ITGA2/ITGB3‐RT), type 2B von Willebrand disease (VWD) and platelet‐type VWD (PT‐VWD) [2, 3, 4]. The gene discussed is ITGB3; the disease is von Willebrand disease type 2B.