The Siwu Decoction can improve the peripheral blood picture of anemic mice, and increase the expression of transferrin receptor/Ly antigen 76, a surface marker antigen on peripheral blood and spleen red blood cells.[96] Its mechanism of improving anemia is related to its ability to regulate iron metabolism by improving ferritin.[97] The above process is related to its protection of liver cells. This evidence concerns the gene TFRC and anemia (phenotype).