Furthermore, recent research has highlighted the importance of detecting PCT levels in the early diagnosis of mycoplasma pneumonia.[20] CRP, an acute-phase reactant protein, begins to elevate 6 to 8 hours postinfection, peaking 24 to 48 hours thereafter, and swiftly declines upon infection resolution, making it an ideal marker for early mycoplasma pneumonia diagnosis.[21] The findings of this study affirm that the combined administration of azithromycin and budesonide with Xiao’er Chiqiao Qingre Granules effectively suppresses the inflammatory response in children with M pneumoniae infection. This evidence concerns the gene CRP and infection.