Serum biomarkers and BMD parameters (femoral neck, trochanter, intertrochanteric region, total hip, and Ward triangle) of the contralateral hip were collected and compared.The intertrochanteric fracture group had significantly lower red blood cell count, hemoglobin, albumin, total cholesterol, and serum calcium levels than the femoral neck fracture group (P < .001), but had higher blood urea nitrogen levels (P = .01). This evidence concerns the gene ALB and bone fracture.