APP and atherosclerosis: Notably, among all EC subtypes, Endo1 cells showed the highest expression of APP (Figure 6G), and APP levels positively correlated with migrasome scores in two independent atherosclerosis datasets (GSE132651 and GSE28829; r = 0.556, p = 0.048; r = 0.597, p = 0.015) (Figure 6H).