Next, we analyzed the published GSE databases from four human chronic fibrotic liver diseases, including MASH (GSE126848),[15] liver cirrhosis (GSE142530),[16] HBV (GSE 84044),[17] Primary Sclerosis Cholangitis (PBC) (GSE 61260).[18] Consistent with our previous findings, liver ChREBP mRNA abundance was significantly reduced in MASH patients. This evidence concerns the gene MLXIPL and cirrhosis of liver.