Inhibition of hepatocyte TGF‐β signaling by deletion of either Tgf‐β receptor 2 (Tgf‐β2) or Smad4 was shown to protect mice from liver inflammation and fibrosis.[9] These findings suggest that inhibition of hepatocyte TGF‐β signaling could be a viable option for reversing liver fibrosis. The gene discussed is TGFB1; the disease is inflammatory response.