SREBF1 and nonpapillary renal cell carcinoma: We then performed ssGSEA of ccRCC data in the TCGA database to identify the infiltration of distinct immune cell subsets affected by SREBP1, and the results indicated that increased expression of SREBP1 was associated with decreased infiltration of natural killer cells and Th17 cells but increased infiltration of Th2 cells (Figure S7B, Supporting Information).