SREBF1 and neoplasm: SREBP1, encoded by SREBP1, is a transcription factor that promotes immunosuppressive (M2‐like) tumor‐associated macrophage (TAM) survival and tumor immune evasion by mediating fatty acid synthesis in M2 macrophages.[38] Furthermore, SREBP1 blockade was found to increase the efficacy of immune checkpoint inhibitors.[38] In this study, we focused on SREBP1 in ccRCC cells to investigate its function in the tumor immune microenvironment.