To determine whether SMYD3 drives tumor immune evasion via CD47 upregulation and subsequent activation of SREBP1 expression, we overexpressed SREBP1 in stable SMYD3‐knockdown 786‐O and TK10 cells to investigate whether the effects of SMYD3 knockdown could be eliminated upon SREBP1 overexpression (Figure 7B,C). This evidence concerns the gene SREBF1 and neoplasm.