RAB18 and obesity disorder: The dynamics of LDs reflect lipid metabolic status, and uncontrolled LD growth has been linked to the initiation of obesity LD biogenesis[28]; furthermore, nascent LDs are formed in the ER.[29, 30] Nascent LDs may become mature LDs by acquiring neutral lipids from the ER through their continuous association with this organelle.[31] RAB18 can promote LD growth by tethering the LDs to the ER through the interactions of SNARE and NRZ.[20] Analysis of the MS and Co‐IP data revealed that βFaar can bind to the GTPase RAB18, and βFaar overexpression significantly reduced the content of RAB18.