The proportions of CD3+T cells (P = 0.005) and CD3+CD8+T cells (P < 0.001) were significantly higher in patients with SLE than in HCs, while the proportion of NK cells (P < 0.001) was significantly lower in patients with SLE than in HCs (Table 2). The gene discussed is CD8A; the disease is systemic lupus erythematosus.