PROS1 and neoplasm: The expression of the antiapoptotic protein BCL2 and proinvasion-related proteins Snail and N-CAD was upregulated in 22RV1 and PC-3 tumor cells, while those of the proapoptotic protein BAX and invasion-related protein E-CAD were downregulated (Figures 5a, 5b, 5c, and 5d).