Cytokines involved in tumor-promoting inflammation including TNF-α, IL-1, IL-6, COX2, iNOS, and MCP1, and factors like Cyclin E, Cyclin D, and proto-oncogen c-Myc are accountable for the activation of the NF-κβ pathway resulting in the cancer cell proliferation (160, 178, 223, 224). Here, NFKB1 is linked to neoplasm.