NFKB1 and neoplasm: The NF-κB signaling cascade is reported to be targeted using ferulic acid, vanillic acid, curcumin, resveratrol, nobiletin, trilobatin, apigenin, cirsiliol, scutellarein, acacetin, chalcone 2, luteolin, anthocyanidin, ginsenoside Rg-3, chlorogenic acid, quercetin, dehydroxymethylepoxyquinomicin (DHMEQ), nepalolide A, and parthenolide (Figure 2), ensuring interruption in tumor growth and proliferation, considering low toxicity to healthy cells (224–239).