In the last week of the study, the bloodglucose levels of the Diabetes + Api3 group decreased to 17.6% and13.5% compared to the Diabetes and Diabetes + Api1 groups (p < 0.01 and p < 0.05, respectively).Administration of Apilarnil doses to rats in the diabetes group didnot reduce blood glucose levels below 200 mg/dL. The gene discussed is XIAP; the disease is diabetes mellitus.