CD8A and cancer: SFV/IFNγ upregulated expression of Ifng, Nos2, H2-Ab1 (MHC II gene), Sting1 and monokine induced by IFNγ (MIG) gene Cxcl9. Increased levels of CXCL9 and CXCL10 have been linked to enhanced infiltration of effector CD8+ T cells in various mouse and human cancers [50].