HMOX1 and glioblastoma: Our study confirms that 4T1-conditioned media induce the expression of M2 markers such as Arg1, Mrc1 (CD206) and Ccl22. Interestingly, similar to previous studies in a glioblastoma mouse model [69], we have found the upregulation of Cdh1 (Figure 4B), Arg1, Mrc1 (Figure 8C) and F13a1, Hmox1 and Il1r2 (Figure S2) gene expression in macrophages after incubation with 4T1 cell CM.